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Features

IAVI announces the onset of first-in-human Phase 1 clinical trial of broadly neutralizing antibodies (bnAbs) to prevent HIV transmission

April 1, 2026

The trial, run by the HIV Vaccines Trial Network (HVTN) and HIV Prevention Trials Network (HPTN), will evaluate the safety, dosing, pharmacokinetics, and ability of four bnAbs to neutralize HIV

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Features

Communities are front and center in TB vaccine advocacy this World TB Day 

March 24, 2026

Updates on IAVI’s advocacy, communications, and programs to advance TB vaccines

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Scientific Publications

Acute and early HIV infection screening among men who have sex with men, a systematic review and meta-analysis

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Scientific Publications

Report of a one-day convening on regulatory science, practices, and innovative approaches to facilitate approval of novel combination vaccines

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Scientific Publications

Local antibody feedback enforces a checkpoint on affinity maturation in the germinal center and promotes epitope spreading

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Features

IAVI announces enrollment of cohort of people without tuberculosis (TB) infection in Phase 2b trial of TB vaccine candidate MTBVAC

February 23, 2026

Additional enrollment of 1,200 participants could ultimately enable a fast track to licensure

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Scientific Publications

Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization

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Scientific Publications

Virus glycoprotein nanodisc platform for vaccine analytics

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