January 19, 2021

IAVI at HIVR4P Virtual 2021

IAVI to participate in major HIV prevention research conference beginning January 27.

IAVI at R4P Virtual 2021 homepage

IAVI is proud to participate in the HIV Research for Prevention Conference 2021 (HIVR4P // Virtual), the world’s only scientific meeting dedicated exclusively to biomedical HIV prevention, hosted by the International AIDS Society (IAS). We join in celebrating the progress made by scientists, advocates, communities, and all who are committed to a world without AIDS.

The conference is a combination of live, recorded, and on-demand presentations across four conference days: January 27-28 and February 3-4. IAVI leaders and researchers will contribute to the programming along with the world’s leading HIV prevention researchers, implementers, and advocates, presenting the latest science across 29 research categories.

At this conference, IAVI has a prominent role in sharing the research and partnership innovations that drive progress on HIV prevention. We have key speaking slots on topics including HIV vaccine development and the potential for use of broadly neutralizing antibodies to prevent HIV. ADVANCE-supported clinical research center partner researchers from many African countries are highlighting strides made in strengthening research capacity in Africa and bringing forward the needs of communities whose health experiences are most often silenced. See the conference program. Before and during the conference, you can follow along on social media with the hashtag #HIVR4P.

Much of the work that IAVI and partner colleagues are presenting at R4P is made possible by the support of the American people through U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) through the United States Agency for International Development (USAID) and by the support of our many other funders.

Below are the ways we are contributing to HIVR4P, together with our partners. Learn more about the conference and register to access conference presentations. And while the conference is happening, follow along on IAVI’s social media channels for live updates.

 

Roundtables, Symposia, Plenaries, and Oral Abstract Sessions

Wednesday, January 27, 16:15 – 17:15 UTC

Roundtable Session: Coming soon to a clinic near you? The antibody infusion pipeline
Co-chair: Kundai Chinyenze, Executive Medical Director, IAVI, Kenya
Presentation title: Optimization of bNAbs for HIV prevention, Devin Sok, Executive Director, Antibody Discovery and Development, IAVI Neutralizing Antibody Center, United States
Code RT01, Live channel 2

Thursday, January 28, 14:00 – 14:45 UTC

Plenary Session: More is better: Expanding the prevention pipeline
Presentation title: Are we getting closer? Preventive vaccines and passive immunization strategies, Mark Feinberg, President & CEO, IAVI, United States
Code PL02, Live channel 1

Thursday, January 28, 17:30 – 18:30 UTC

Oral Abstract Session: Integrating and optimizing cellular responses
Presentation title:
Spontaneous in vivo control of HIV replication is underpinned by the cross-clade antiviral potency of HIV-specific CD8 T cells, Julia Makinde, Research Associate IAVI, United Kingdom
Code OA09, Live channel 1

Thursday, January 28, 17:30 – 18:30 UTC

Oral Abstract Session: Mapping policy: Accelerating progress locally, nationally and globally
Presentation title: Pathways to global access for novel HIV prevention technologies, Shelly Malhotra, Senior Director, Global Access, IAVI, United States
Code OA10, Live channel 2

Wednesday, February 3, 15:00 – 16:00 UTC

Oral Abstract Session: Pathways to maintaining HIV latency and suppression
Presentation title: Analysis of the early responses to HIV-1 in matched treatment naïve individuals reveals early soluble proteins that are associated with in vivo virus control, Julia Makinde, Research Associate, IAVI, United Kingdom
Code OA14, Live channel 3

Wednesday, February 3, 11:15 – 12:15 UTC

Oral Abstract Session: In the beginning: Virus-host cell interactions
Presentation title: Transmitted found viruses: The sequences we’re facing, Gladys Macharia, Postdoctoral Research Scientist, IAVI, United Kingdom
Code SY06, Live channel 1

Wednesday, February 3, 16:15 – 17:15 UTC

Symposium Session: Early vaccine clinical studies on native-like envelope trimers and germline-targeting immunogens
Presentation title: Germline-targeting of the CD4 binding site by eOD-GT8, William Schief, Executive Director of Vaccine Design, IAVI Neutralizing Antibody Center; Professor, Department of Immunology and Microbiology, Scripps Research, United States
Code SY07, Live channel 2

Presentation title: Immunogenicity of the prototype native-like trimer BG505 SOSIP.664, Gaudensia Mutua, Medical Director, IAVI, Kenya

Wednesday, February 3, 17:30 – 18:30 UTC

Oral Abstract Session: Community engagement: Enabling responsive, inclusive, accountable research
Co-chair: Jauhara Nanyondo, Associate Director of Community Engagement, IAVI, Uganda
Presentation title: Redefining ownership: the mismatch between female sex workers’ research priorities and the field in Kenya, George Victor Owino, Program Manager, IAVI, Kenya
Code OA17, Live channel 3

 

Satellites

Wednesday, January 27, 18:45 – 20:15 UTC

Symposium Session: HIV & TB: An R&D tale of two vaccines
Co-sponsors: International AIDS Society, TBVI
Participants: IAVI; International AIDS Society, TBVI, others TBA.
IAVI speaker: Kundai Chinyenze, Executive Medical Director, IAVI, Kenya
IAVI speaker topic: A short and long view of the HIV vaccine pipeline
Code SA03, Live channel 2

Thursday, January 28, 12:45 – 13:45 UTC

Symposium Session: Engaging Lake Victoria Fishing Communities in HIV Prevention Research: Lessons from Uganda, Kenya, and Tanzania
Co-sponsor: Lake Victoria Consortium for Health Research
Participants: IAVI; Medical Research Council/Uganda Virus Research Institute; Mwanza Interventions Trials Unit; London School of Hygiene and Tropical Medicine; Research Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute; U.S. Military HIV Research Program
IAVI speaker: Vincent Muturi-Kioi, Medical Director, IAVI, Kenya
IAVI speaker topic: Prevention of co-enrollment in clinical trials recruiting volunteers from Lake Victoria fishing communities
Code SA07, Live channel 3

Wednesday, February 3, 12:15 – 13:45 UTC

Symposium Session: Helping data talk to you: The power of open access data sources
Sponsors: IAVI-Human Immunology Laboratory, Imperial College London; USAID
Participants: EPFL; IAVI; Imperial College London; National Institutes of Health; Tableau Software; Uganda Virus Research Institute, London School of Hygiene and Tropical Medicine; University of Manitoba; University of Oxford
IAVI speakers: Jonathan Hare, Glady Macharia, Julia Makinde, Manj Sandhu
IAVI speaker topics: Overview of IAVI ADVANCE DataSpace (Sandhu); Visualizations of Protocol C data as a tool for facilitating novel research (Hare); Utilizing the IAVI DataSpace to drive research project (Makinde); Using the IAVI DataSpace to select HIV sequences for further characterization (Macharia)
Code SA13, Live channel 3

Wednesday, February 3, 18:45 – 20:15 UTC

Symposium Session: Engagement of African Men and Transgender Women Who Have Sex with Men in HIV Research
Co-sponsors: IAVI, Men’s Health Research Consortium, U.S. Military HIV Research Program
Participants: Advocates for HIV Prevention and AIDS in Africa; Emory University, Rolling School of Public Health; Harvard T.H. Chan School of Public Health; IAVI; Initiative Sankofa D’Afrique de L’ouest; Johns Hopkins Bloomberg School of Public Health; Kenya Medical Research Institute Wellcome Trust Programme; University of Manitoba, Department of Community Health Sciences; University of Maryland, Maryland Global Initiative Corporation; University of Washington, Departments of Global Health and Medicine
IAVI speaker: Shaun Palmer, Communications Associate, IAVI, Netherlands
IAVI speaker topic: Innovative strategies for engaging and retaining African MSM: Mobilization to diagnose HIV earlier in African MSM
Code SA15, Live channel 1

Advocates’ Corner

IAVI will be leading and participating in several activities in the Advocates’ Corner.

In particular, with AVAC and the CASPR Coalition, we are co-hosting The Advocates’ Dialogue on DRM for R&D, which seeks to provide a platform for HIV prevention advocates and civil society organizations to discuss domestic financing of HIV research and development on continent and share experiences and perspectives on advocacy for domestic resource mobilization for HIV R&D and the impact of COVID-19 on future funding for HIV R&D.

Watch our social channels for more information on our Advocates’ Corner sessions.

Posters and Publications

Additionally, many researchers are representing IAVI, ADVANCE, and partners in the posters and publications listed below.

Title Presenter Type
Comparison of HIV incidence in simulated vaccine efficacy trials and observational cohorts using propensity scores in key populations in Uganda Abaasa Publication
HIV testing access outside a trial centre among vaccine recipients despite counselling on possible vaccine induced sero positivity (VISP): experience from a research centre in western Uganda Asio E-poster
Breadth of CD8 T-cell mediated inhibition of HIV-1 replication correlates with breadth of epitope recognition mapped with a comprehensive Gag, Nef, Env and Pol potential T-cell Epitope (PTE) peptide set Fernandez E-poster
Generation of HIV-specific CD4 and CD8 T-cell clones for use in HIV viral inhibition assays Fernandez Publication
Effect of a novel HIV-1 RNA testing intervention to detect acute and prevalent HIV infection in young adults and reduce HIV transmission in Kenya: A randomized controlled trial Graham E-poster
Variation in neutralization susceptibility of HIV-1 Indian subtype C to potent and broadly neutralizing monoclonal antibodies (bnAbs) having distinct epitope specificities Hingankar E-poster
Pre-exposure prophylaxis (PrEP) uptake and adherence in gays, bisexuals and transgender women (GBT): qualitative insights from PrEP users, providers and GBT leadership in coastal Kenya Kimani E-poster
The impact of human immunodeficiency virus-1 viral replicative capacity on infection of human cervical and rectal tissue explants ex vivo Langat E-poster
Willingness of adolescent girls and young women in Kampala, Uganda to participate in future efficacy trials of novel biomedical HIV prevention interventions: the anti-retroviral implant Mayanja Publication
Low prevalence of likely depression among PrEP users in Kenya Mogere Publication
Challenges of conducting a simulated vaccine efficacy trial (SiVET) in fishing communities of Lake Victoria in Uganda Nakaweesa Publication
Origin, diversity, and spread of HIV-1 infection in Kenya Nduva E-poster
Computer Assisted Self Interviews (CASI) among high risk women in fishing communities on Lake Victoria: HPTN 084 EXPERIENCE Odenyo E-poster
Using participatory action research tools to understand gender dynamics in uptake of HIV prevention measures and participation in research: insights through a road-block mapping exercise Saha E-poster
Increased frequency of inter-subtype HIV-1 recombinants identified by near full-length virus sequencing in a Rwanda acute heterosexual transmission cohort Yue Publication