Incidence / prospective cohort
Projet San Francisco (PSF-Kigali), Kigali, Rwanda; Zambia-Emory HIV Research Project (ZEHRP)-Lusaka, Zambia; Zambia-Emory HIV Research Project (ZEHRP)-Copperbelt, Zambia; Zambia-Emory HIV Research Project (ZEHRP)-Ndola, Zambia.
To estimate the annual incidence of HIV infection, characterize early HIV infection, and prepare clinical trial sites for HIV preventive vaccine efficacy trials for which volunteers from this study cohort may be recruited. Since 1986 in Kigali, 1994 in Lusaka, and 2004 in Ndola, consenting HIV discordant couples have been followed quarterly and provided specialized counseling that includes risk reduction and condom advocacy. IAVI support began in 2004 and completed in 2012.