Incidence / prospective cohort
Kenya AIDS Vaccine Initiative-Kangemi (KAVI-Kangemi), Nairobi, Kenya; Kenya AIDS Vaccine Initiative-Kenyatta National Hospital (KAVI-KNH), Nairobi, Kenya
To assess vaccine-induced mucosal HIV-1-specific immune responses in volunteers concurrently enrolled in HIV preventive vaccine trials
To determine volunteers’ acceptance of mucosal sampling methodsTo help establish the reproducibility and validity of methods of assessing vaccine-induced mucosal HIV-1-specific immune responses.
To compare vaccine-induced systemic HIV-1-specific immune responses with HIV-1-specific immune responses at mucosal surfaces