Type: Prospective mucosal sampling sub-study attached to IAVI-sponsored clinical trials, 89 volunteers enrolled
Study Status: Completed
Enrollment Status: Closed
Countries: Kenya
Partners: KAVI-Institute of Clinical Research, Kangemi, Nairobi, Kenya; KAVI-Institute of Clinical Research, Kenyatta National Hospital, Nairobi, Kenya

Study Summary:
To assess vaccine-induced mucosal HIV-1-specific immune responses in volunteers concurrently enrolled in HIV preventive vaccine trials.

Secondary Objectives:
To determine volunteers’ acceptance of mucosal sampling methods to help establish the reproducibility and validity of methods of assessing vaccine-induced mucosal HIV-1-specific immune responses.
To compare vaccine-induced systemic HIV-1-specific immune responses with HIV-1-specific immune responses at mucosal surfaces