Type: Prospective mucosal sampling sub-study attached to IAVI-sponsored clinical trials, 89 volunteers enrolled
Enrollment Status: Closed
Partners: KAVI-Institute of Clinical Research, Kangemi, Nairobi, Kenya; KAVI-Institute of Clinical Research, Kenyatta National Hospital, Nairobi, Kenya
To assess vaccine-induced mucosal HIV-1-specific immune responses in volunteers concurrently enrolled in HIV preventive vaccine trials.
To determine volunteers’ acceptance of mucosal sampling methods to help establish the reproducibility and validity of methods of assessing vaccine-induced mucosal HIV-1-specific immune responses.
To compare vaccine-induced systemic HIV-1-specific immune responses with HIV-1-specific immune responses at mucosal surfaces