IAVI conducts clinical trials, observational epidemiology, and sociobehavioral research that informs the design of vaccine candidates and other prevention modalities. This work also provides important data for future efficacy trials to prevent HIV and other diseases of global public health significance. IAVI works with academic, government, foundation, and community-based partners to conduct this research.
IAVI’s network of clinical research partners in sub-Saharan Africa, India, and the U.K. play a central role in our clinical research.
IAVI supports the development of in-country scientific and technical expertise and leadership needed to conduct research at the highest ethical and scientific standards. IAVI also implements the concepts of Good Participatory Practice Guidelines to ensure community engagement throughout the research process.
IAVI’s key clinical research activities:
- Test novel vaccines and antibodies from preclinical research through Phase I-III clinical trials. This includes products against HIV, SARS-CoV2, tuberculosis, Lassa fever, snakebite, and others.
- Prepare to execute efficacy trials in at-risk populations through supportive epidemiology and capacity building, as well as stakeholder and community engagement.
- Develop in-country scientific capacity and leadership in the HIV research field, including HIV vaccine design and development through a wide range of collaborative and education programs.