PMID: 19863673
Title: Vaccination with SIVmac239Deltanef activates CD4 T cells in the absence of CD4 T cell loss
Abstract: Pathogenic HIV and SIV infections characteristically deplete central memory CD4(+) T cells and induce chronic immune activation, but it is controversial whether this also occurs after vaccination with attenuated SIVs and whether depletion or activation of CD4(+) T-cell play roles in protection against wild-type virus challenge.
Date: 1970-08-21
Year: 2010
Journal: J. Med. Primatol.
PMID Author: Reeves RK, Gillis J, Wong FE, Johnson RP
PMC Link #: PMC2810497
Vaccination with SIVmac239Deltanef activates CD4+ T cells in the absence of CD4 T-cell loss. J. Med. Primatol. 2009;38 Suppl 1:8-16 doi: 10.1111/j.1600-0684.2009.00370.x

Media Contacts

Africa

Ethel Makila
+254 71 904 3142
EMakila@iavi.org

 

Europe

Hester Kuipers
+31 20 521 0343
HKuipers@iavi.org 

 

Global

Anita Kawatra
+1 212 847 1055
AKawatra@iavi.org 

 

India

Saif ul Hadi
+91 11 4737 6032
SulHadi@iavi.org 

 

United States

Rose Catlos
+1 212 847 1049
RCatlos@iavi.org