PMID: 30857933
Title: Simulated vaccine efficacy trials to estimate HIV incidence for actual vaccine clinical trials in key populations in Uganda
Abstract: Fisherfolks (FF) and female sex workers (FSW) in Uganda could be suitable key populations for HIV vaccine efficacy trials because of the high HIV incidence and good retention in observational cohorts. However, the observed HIV incidence may differ in participants who enroll into a trial. We used simulated vaccine efficacy trials (SiVET) nested within observational cohorts in these populations to evaluate this difference.
Date: 1970-08-22
Year: 2019
Journal: Vaccine
PMID Author: Abaasa A, Nash S, Mayanja Y, Price M, Fast PE, Kamali A, Kaleebu P, Todd J
IAVI Topics: Capacity Building and Research Preparedness, IAVI Clinical Trial
IAVI Keywords: HT Study, Fishing Communities

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