Deciphering the human immunome

Expert Rev Vaccines. 2015;14(11):1421-5. doi: 10.1586/14760584.2015.1082427. Epub 2015 Aug 24.

Abstract

Technological advances in next-generation DNA sequencing offer great potential to probe the human immune system. On 3 April 2015, leading immunologists and bioinformatics scientists met to consider how best to harness these advances for decoding the human immunome.

Keywords: B-cell and T-cell receptors; antigen-specific repertoires; bioinformatics; human immunome; vaccines and immunotherapeutics.

MeSH terms

  • Adaptive Immunity / genetics*
  • Computational Biology / methods*
  • High-Throughput Nucleotide Sequencing / methods*
  • Humans
  • Immunity, Innate / genetics*