Deciphering the human antigenome

Expert Rev Vaccines. 2016;15(2):167-71. doi: 10.1586/14760584.2016.1112743. Epub 2015 Dec 2.

Abstract

Recent technological advances in genomics, mass spectrometry, and epitope identification algorithms offer significant potential to identify novel antigenic targets for vaccine and immunotherapeutic development. On 30 April 2015, leading immunologists and bioinformatics scientists met to consider how best to utilize these advances towards deciphering the human antigenome and exploiting this information for prevention and control of infectious and neoplastic diseases.

Keywords: Human vaccines project; T cells; antibodies; antigenome; bioinformatics; epitopes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens / immunology*
  • Computational Biology / methods*
  • Genome, Human*
  • Genomics / methods*
  • Humans
  • Proteomics / methods*

Substances

  • Antigens