Characterization of a core fragment of the rhesus monkey TRIM5 protein
Like all tripartite motif (TRIM) proteins, the retroviral restriction factor TRIM5α consists of RING, B-box 2 and coiled-coil domains, with a C-terminal B30.2(SPRY) domain. Although structures have been determined for some individual TRIM domains, the structure of an intact TRIM protein is unknown.
- PMID Author:
Kar AK, Mao Y, Bird G, Walensky L, Sodroski J
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