How do viral and host factors modulate the sexual transmission of HIV? Can transmission be blocked?

PLoS Med. 2006 Feb;3(2):e79. doi: 10.1371/journal.pmed.0030079. Epub 2006 Feb 28.

Abstract

A better understanding of sexual transmission, say the authors, will enable more rational design of vaccines and microbicides and potential combinations of the two.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • AIDS Vaccines / immunology
  • Antibody Formation
  • Disease Susceptibility
  • Female
  • HIV / pathogenicity*
  • HIV Infections / prevention & control*
  • HIV Infections / transmission*
  • Humans
  • Immunity, Mucosal
  • Male
  • Rectum / virology
  • Sexually Transmitted Diseases / immunology
  • Sexually Transmitted Diseases / transmission*
  • Sexually Transmitted Diseases / virology
  • Vagina / virology
  • Viral Load
  • Virus Replication

Substances

  • AIDS Vaccines