PMID: 30885692
Title: Adeno associated virus vectored immunoprophylaxis to prevent HIV in healthy adults a phase 1 randomised controlled trial
Abstract: A preventive vaccine for HIV is a crucial public health need; adeno-associated virus (AAV)-mediated antibody gene delivery could be an alternative to immunisation to induce sustained expression of neutralising antibodies to prevent HIV. We assessed safety and tolerability of rAAV1-PG9DP, a recombinant AAV1 vector encoding the gene for PG9, a broadly neutralising antibody against HIV.
Date: 1970-08-21
Year: 2019
Journal: Lancet HIV
PMID Author: Priddy FH, Lewis DJM, Gelderblom HC, Hassanin H, Streatfield C, LaBranche C, Hare J, Cox JH, Dally L, Bendel D, Montefiori D, Sayeed E, Ackland J, Gilmour J, Schnepp BC, Wright JF, Johnson P
IAVI Topics: IAVI Clinical Trial
IAVI Keywords: IAVI A003

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