Early Infection Cohorts: Insights for Design of Vaccines and Other Interventions

Monday, 27 October
Time: 08:30-12:30
Venue: CTICC Room 1.43-1.44
Hosting partners:
     International AIDS Vaccine Initiative (IAVI)
     University of KwaZulu-Natal (UKZN)
Jill Gilmour, Executive Director, IAVI Human Immunology Laboratory
Thumbi Ndung’u, Scientific Director, HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal

Studies of early HIV infection with longitudinal follow-up have contributed in many ways to our understanding of the epidemic: the clinical course of infection; risk factors; potential public health, behavioral and structural interventions; the nature of transmitted viruses; the interplay of host immune response and genetics with viral variation/escape; 
the evolution of broadly neutralizing antibodies, and much more.

This satellite will review a number of the major cohorts and key findings from these studies, emphasizing research insights that apply to vaccine design as well as their potential value for other prevention and treatment methods. Representatives from major research organizations conducting these cohorts will present their studies and findings and we will have an open, moderated discussion of outstanding research questions and the clinical studies needed to address them. With this session, we hope to frame the questions and facilitate the collaborations that will move us closer to a vaccine.