Neutralizing Antibody Consortium (NAC)
broadly neutralizing anti-HIV antibodies (bNAbs) in the hope of reverse engineering vaccines on the basis of what was learned about their interactions with HIV.
Since 2009, thanks in large measure to the efforts of the NAC, more than two dozen bNAbs have been isolated from volunteers around the world. The structures of some of the most potent of these antibodies and their targets have also been solved. These discoveries are now being applied to the design of novel AIDS vaccine candidates.
The NAC is led by Scientific Director Dennis Burton. Members include researchers from leading HIV research labs and clinical research centers around the world. In 2009, IAVI and The Scripps Research Institute established the IAVI Neutralizing Antibody Center at The Scripps Research Institute in La Jolla, Calif., as the headquarters for the NAC.