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VRC01LS

NCT02599896

Trial Details:

I Ongoing
National Institute of Allergy and Infectious Diseases (NIAID)
VRCHIVMAB080-00-AB
Healthy adults
RandD/trials/Lists/ClinicalTrialsList
8/1/2017
VRC01-LS is the VRC01 mAb modified by site-directed mutagenesis to increase its binding affinity for FcRn.
VRC-HIVMAB080-00-AB (VRC01LS) 5 mg/kg/IV on Day 0 5 mg/kg SC on Day 0 20 mg/kg IV on Day 0 40 mg/kg IV on Day 0 5 mg/kg SC on Day 0, Week 12 and Week 24 20 mg/kg IV on Day 0, Week 12 and Week 24 ? VRC-HIVMAB060-00-AB (VRC01) 5 mg/kg SC on Day 0, Week 4 20