Published Research

 

IAVI routinely supports original research in a wide variety of fields including scientific and clinical research as well as policy analysis and sociological study in support of AIDS vaccine development. Much of this work is conducted in collaboration with our partners worldwide.  This section highlights the articles written by IAVI staff and/or IAVI-sponsored research that have been published in peer-reviewed and other highly-regarded journals.

Recent Articles Authored by IAVI Staff

Indian journal of medical research: Safety & immunogenicity of tgAAC09, a recombinant adeno-associated virus type 2 HIV-1 subtype C vaccine in India

Published: 2010

Background & objective: A phase 1 trial of adeno-associated virus based HIV-1 subtype C vaccine (tgAAC09) was conducted at two sites in Germany and Belgium and one site in India. This paper reports the safety and immunogenicity of tgAAC09 in healthy adult ...

PLoS pathogens : A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals

Published: 2010

A protective vaccine against HIV-1 will likely require the elicitation of a broadly neutralizing antibody (bNAb) response. Although the development of an immunogen that elicits such antibodies remains elusive, a proportion of HIV-1 infected individuals evo...

AIDS research and human retroviruses: A Phase 2 Study to Evaluate the Safety and Immunogenicity of a Recombinant HIV Type 1 Vaccine Based on Adeno-Associated Virus.

Published: 2010

Abstract The recombinant vaccine, tgAAC09, based on an adeno-associated virus serotype 2 (AAV2) vector encoding HIV-1 subtype C Gag, protease, and part of reverse transcriptase, induced robust T cell and antibody responses in nonhuman primates. In a previo...

New england journal of medicine: The Renaissance in HIV Vaccine Development

Published: 2010

From July 18 through July 23, 2010, delegates from around the globe will convene for the biennial International AIDS Conference in Vienna. They will discuss our current risk of losing the war against the human immunodeficiency virus (HIV). Despite an unpre...


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