InternationalClinical Trials
IAVI and its partners have conducted dozens of studies to advance the development of safe and effective AIDS vaccines. This database provides information on IAVI-supported clinical trials of preventive HIV vaccine candidates.
IAVI-Sponsored Studies
24
| Study Name | Phase | Status | Strategies | Candidates | Countries | Volunteers | Partners | |
|---|---|---|---|---|---|---|---|---|
| IAVI T001 | I | Ongoing | Passive Immunization | PGT121 | USA | 63 | Show Partners | |
| IAVI R001 | I | Completed | Replicating Vector |
rcAd26.MOS1.HIV-Env |
USA |
24
|
Show Partners | |
| IAVI S001 | I | Completed | Replicating Vector | SeV-G(NP) | United Kingdom Kenya Rwanda |
65
|
Show Partners | |
| IAVI A003 | I | Ongoing | Vectored Immuno-prophylaxis | rAAV1-PG9DP | United Kingdom |
24
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Show Partners | |
| IAVI 001 | I | Completed | DNA | DNA.HIVA | United Kingdom |
18
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Show Partners | |
| IAVI P002 | I | Completed | DNA ; Viral Vector - Pox | TBC-M4; ADVAX | United Kingdom |
32
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Show Partners | |
| IAVI 002 | I | Completed | DNA | DNA.HIVA | Kenya |
18
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Show Partners | |
| IAVI 010 | IIa | Completed | DNA ; Viral Vector - Pox | DNA.HIVA MVA.HIVA | Kenya United Kingdom |
115
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Show Partners | |
| IAVI 011 | I | Completed | Viral Vector - Pox | MVA.HIVA | South Africa United Kingdom Switzerland |
81
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Show Partners | |
| IAVI A001 | I | Completed | Viral Vector - Adeno-associated Virus | tgAAC09 | Belgium Germany India |
80
|
Show Partners | |
| IAVI A002 | II | Completed | Viral Vector - Adeno-associated Virus | tgAAC09 | South Africa Uganda Zambia |
91
|
Show Partners | |
| IAVI C002 | I | Completed | Viral Vector - Pox | ADMVA | USA |
48
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Show Partners | |
| IAVI C003 | I | Completed | Viral Vector - Pox | ADMVA | USA |
8
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Show Partners | |
| IAVI C004/DHO-614 | I | Completed | DNA | ADVAX | USA |
40
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Show Partners | |
| IAVI D001 | I | Completed | Viral Vector - Pox | TBC-M4 | India |
32
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Show Partners | |
| IAVI V001 | I | Completed | DNA, Viral Vector - Pox | VRC-HIVDNA016-00-VP,VRC-HIVADV014-00-VP | Kenya Rwanda |
114
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Show Partners | |
| IAVI B001 | I | Completed | Viral Vector - Adeno | Ad35-GRIN, Ad35-GRIN/ENV | USA |
56
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Show Partners | |
| IAVI P001 | I | Completed | DNA, Viral Vector - Pox | ADVAX, TBC-M4 | India |
32
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Show Partners | |
| IAVI 016 | I | Completed | Viral Vector - Pox ; DNA | MVA.HIVA ; DNA.HIVA | United Kingdom |
24
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| IAVI 003 | I | Completed | Viral Vector - Pox | MVA.HIVA | United Kingdom |
8
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Show Partners | |
| IAVI 004 | I | Completed | Viral Vector - Pox | MVA.HIVA | Kenya |
18
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Show Partners | |
| IAVI 005 | I | Completed | Viral Vector - Pox; DNA | MVA.HIVA; DNA.HIVA | United Kingdom |
9
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| IAVI 008 | I | Completed | Viral Vector - Pox | MVA.HIVA | Kenya |
10
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Show Partners | |
| IAVI 009 | I | Completed | DNA; Viral Vector - Pox | DNA.HIVA ; MVA.HIVA | Uganda |
50
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Show Partners | |
| IAVI C001 | I | Completed | DNA | ADVAX | USA |
45
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Show Partners | |
| IAVI B003 | I | Completed | Viral Vector - Adeno | Ad26.EnvA-01; Ad35-ENV | USA Kenya Rwanda South Africa |
218
|
Show Partners | |
| IAVI B002 | I | Completed | Protein; Viral Vector - Adeno | Adjuvanted GSK investigational HIV vaccine formulation 1; Adjuvanted GSK investigational HIV vaccine formulation 2; Ad35-GRIN | Kenya Uganda Zambia |
147
|
Show Partners | |
| IAVI B004 | I | Completed | DNA, Viral Vector - Adeno | HIV-MAG +GENEVAX® IL-12, Ad35-GRIN/ENV | Kenya Uganda Rwanda |
75
|
Show Partners | |
| IAVI 006 | I/II | Completed | DNA; Viral Vector - Pox | DNA.HIVA ; MVA.HIVA | United Kingdom |
120
|
Show Partners | |
| IAVI V002 | II | Withdrawn | DNA, Viral Vector - Adeno | VRC-HIVDNA016 -00-VP, VRC-HIVADV014 -00-VP | Kenya Rwanda Uganda Zambia |
0
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| PAVE 100 | IIb | Withdrawn | DNA, Viral Vector - Adeno | VRC-HIVDNA016 -00-VP, VRC-HIVADV014 -00-VP | USA |
0
|
Other IAVI-Supported Studies
| Study Name | Phase | Status | Strategies | Candidates | Countries | Volunteers | Partners |
|---|---|---|---|---|---|---|---|
| X001
Imperial College London Sponsored |
I | Completed | Protein | CN54gp140 | UK |
12
|
IAVI |
| N004 (HIVCORE 004)
University Oxford Sponsored |
I/IIa | Completed | DNA; Viral Vector - Adeno; Viral Vector - Pox | Ad35-GRIN; MVA.HIV-consv pSG2.HIVconsv-DNA |
Kenya |
72
|
IAVI |
| IDEA EV06
EuroVacc Foundation Sponsored |
I | Completed | DNA, Protein | DNA-HIV-PT123; AIDSVAX B/E
|
Uganda |
72
|
IAVI |
|
Crucell Holland BV Sponsored |
I | Ongoing | Viral Vector - Adeno, Protein | Ad26.Mos.1.Env + Ad26.Mos1.Gag-Pol + Ad26.Mos2.Gag-Pol ; gp140 DP |
USA; Rwanda; South Africa; Thailand; Uganda |
400
|
IAVI |
