Enhancing Brazil's Capacity for Biopharmaceutical Innovation: Advancing the Global Search for an AIDS Vaccine

Published: 2010

This policy brief, produced through a collaboration between IAVI, the Brazilian Association of Collective Health, and the Brazilian National AIDS Department, explores how targeted policy reforms focusing on collaboration, product development capacity, and financing and regulatory coordination could accelerate Brazil’s participation in AIDS vaccine R&D.

From Research Volunteers to the Global Political Community: Building on Preparedness Efforts for the Development of an AIDS Vaccine

Published: 2010

Vaccine preparedness is a comprehensive, partnership-based approach to help countries and communities involved in AIDS vaccine research and to generate support for such efforts in the global community.  This brief describes IAVI’s approach to vaccine preparedness and the core strategies used to meet the challenges of conducting this work in low-income countries hit hardest by HIV.

Adapting to Realities: Trends in HIV Prevention Research Funding 2000 to 2008 - Vaccines Summary

Published: July 2009

This document summarizes 2008 estimates of public, philanthropic, and commercial investment in research and development (R&D) for AIDS vaccines. These estimates were generated through a collaborative project involving the AIDS Vaccine Advocacy Coalition (AVAC), the Alliance for Microbicide Development (AMD), the International AIDS Vaccine Initiative (IAVI), and the UNAIDS Resource Tracking Unit. More information on the HIV Vaccines and Microbicides Resource Tracking Working Group can be found at http://www.hivresourcetracking.org/ .

AIDS Vaccine Q & A

Published: 2009

This listing of questions and answers provides basic information on vaccines and addresses how an AIDS vaccine would work, how AIDS vaccines are tested and why scientists believe the development of an AIDS vaccine is possible .

Innovative Financing Mechanisms to Advance Global Health

Published: June 2009

This policy brief reviews recent innovations in health financing and new options under consideration to address current funding gaps that deter efforts to improve health in resource-limited countries.  Note: Revised version posted on July 15, 2009.

Spurring Innovation for the Development of HIV and AIDS Technologies

Published: April 2009

This report explores a variety of mechanisms seeking to generate solutions to global health problems, including the need for new HIV and AIDS technologies. It includes recommendations on how to move forward in creating an appropriate enabling environment for innovative ideas and approaches     .

Spurring Innovation in AIDS Vaccine R&D: What Will it Take?

Published: April 2009

This brief explores a variety of mechanisms seeking to generate solutions to global health problems, including the need for new HIV and AIDS technologies. It includes recommendations on how to move forward in creating an appropriate enabling environment for innovative ideas and approaches.

VaxLit Core Content 2nd Edition

Published: December 2009

Provides easy to understand information about AIDS vaccines-- from basic science and clinical trials, to social and ethical issues related to vaccine development and testing, as well as future access and use .

VaxLit Toolkit

Published: 2009

The objective of the AIDS Vaccine Literacy (VaxLit) Initiative is to disseminate consistent, comprehensive training and educational materials on AIDS vaccines and clinical trials. VaxLit translates complex technical information into simple language, enabling us to reach audiences who do not have extensive knowledge in the AIDS vaccine field, such as potential trial participants, civil society, medical professionals and media. A VaxLit Toolkit has been developed and contains a number of resources that can be used for training, mobilization, and advocacy activities. The Toolkit includes:

• Core Content – “reference manual” containing basic information about AIDS vaccine development and clinical trials in simple language and format;
• Training Manual – for use by trainers who wish to conduct participatory training workshops about concepts contained in the Core Content;
• Fact sheets – A set of three short 4-page sheets with key information from the Core Content
• PowerPoint slides – presentations outlining information contained in the Core Content; may be useful for presentations, workshops, etc. to deliver basic information to non-technical stakeholders;
• CD-ROM – contains all Toolkit materials in electronic form, in a user-friendly interactive format

AIDS Vaccine Development in Japan

Published: 2008

IAVI is working to ensure that AIDS vaccines are a global priority and that a future vaccine will be accessible to all who need it. In 2007, a new partnership between IAVI and Japanese researchers was launched to develop a recombinant Sendai Virus (Sev) vector vaccine, which has potential to elicit mucosal immunity in people. If successful, the SeV vector-based AIDS vaccine will be the first candidate developed in Japan that will advance to human clinical trials.