AIDS Vaccine Q & A

Published: 2009

This listing of questions and answers provides basic information on vaccines and addresses how an AIDS vaccine would work, how AIDS vaccines are tested and why scientists believe the development of an AIDS vaccine is possible .

Clinical Guidance: Essential Approaches for the Conduct of IAVI Clinical Research

Published: 2009

This document outlines essential processes and practices required to conduct IAVI-sponsored research, based on the specific research and sociocultural context and the needs of the research team, study volunteers, and community. This guidance applies to
clinical trials and to observational and behavioural research studies to ensure that the research itself and associated capacity building efforts and service delivery activities meet high ethical and quality standards.

Integrating Gender Issues into AIDS Vaccine Clinical Research: A Training Manual for Sub-Saharan Africa

Published: 2009

This training manual aims to help improve awareness and understanding of the gender issues relevant to AIDS vaccine clinical research.   It is intended to serve as a resource for trainers with background knowledge or experience in gender issues, AIDS vaccine research and participatory training.

Social Sciences and AIDS vaccine research: The South African experience

Published: December 2009

Social science research is a critical component of many of IAVI’s vaccine development partnerships.  This document describes the IAVI-supported social and behavioral studies done by the Desmond Tutu HIV Foundation and The Aurum Institute in South Africa.  It also explains how the insights gleaned from such studies are applied to refine the conduct of clinical research critical to AIDS vaccine development.

VaxLit Presentations

Published: 2009

Eleven PowerPoint presentations have been created to outline information contained in each chapter of the Core Content. The Vaccine Literacy approach is hinged on innovative techniques to reach diverse audiences in effective ways.  At times, if a didactic approach is preferred, Toolkit users may wish to present information in Power Point format.  The presentations have been developed in the same style of the Core Content, to present information in simple terms. This PDF is a synopsis of the eleven modules.

VaxLit Toolkit

Published: 2009

The objective of the AIDS Vaccine Literacy (VaxLit) Initiative is to disseminate consistent, comprehensive training and educational materials on AIDS vaccines and clinical trials. VaxLit translates complex technical information into simple language, enabling us to reach audiences who do not have extensive knowledge in the AIDS vaccine field, such as potential trial participants, civil society, medical professionals and media. A VaxLit Toolkit has been developed and contains a number of resources that can be used for training, mobilization, and advocacy activities. The Toolkit includes:

• Core Content – “reference manual” containing basic information about AIDS vaccine development and clinical trials in simple language and format;
• Training Manual – for use by trainers who wish to conduct participatory training workshops about concepts contained in the Core Content;
• Fact sheets – A set of three short 4-page sheets with key information from the Core Content
• PowerPoint slides – presentations outlining information contained in the Core Content; may be useful for presentations, workshops, etc. to deliver basic information to non-technical stakeholders;
• CD-ROM – contains all Toolkit materials in electronic form, in a user-friendly interactive format

Current HPV Vaccines and Future AIDS Vaccines: Common Challenges and Unprecedented Opportunities

Published: November 2008

This brief discusses how ensuring swift and efficient HPV vaccine introduction in developing countries will not only help address the burden of cervical cancer, but will also provide a valuable opportunity for AIDS vaccine researchers and advocates to learn from the HPV vaccine experience in planning for the introduction of future AIDS vaccines.

Establishing Clinical Laboratory Reference Intervals in Africa: A Cross-Sectional, Observational Study in Healthy Adults at Multiple African Research Centers

Published: December 2008

This resource reports on a multi-center, clinical laboratory study that characterizes local laboratory reference intervals among healthy adult volunteers in Rwanda, Uganda, Kenya and Zambia. It provides hematology and clinical chemistry analytes, compared to US derived reference intervals; data by research center and gender; and methods and results for generating consensus reference intervals using US CLSI Guidelines.

The Journey Towards An AIDS Vaccine: Perspectives on Conducting Trials in Developing Countries

Published: January 2008

This paper summarizes the broad range of impacts AIDS vaccine studies have had, at individual, community, national, and global levels, above and beyond their value in increasing scientific knowledge.

The Journey Towards An AIDS Vaccine: Perspectives on Conducting Trials in Developing Countries

Published: December 2008

This paper highlights the broad range of impacts AIDS vaccine studies have had, at individual, community, national, and global levels, above and beyond their value in increasing scientific knowledge .