http://www.hivvaccineenterprise.org/conference/2012/
The AIDS Vaccine conference is the largest and most diverse international meeting of researchers, advocates, clinicians, private sector partners and public health experts working collaboratively to advance HIV vaccine science. The following is a list of presentations IAVI and its partners delivered at AIDS Vaccine 2012.
Satellite Session
Title: HIV Vaccine Efficacy Trials: What does it take?
Host Institutions: Global HIV Vaccine Enterprise, AVAC, Fenway Health, Harvard Center for AIDS Research, HIV Vaccine Trials Network, International AIDS Vaccine Initiative, US Military HIV Research Program, NIAID, Ragon Institute and USAID
Session Chair: Margaret McCluskey, USAID
Details: This session provided a general overview of the latest advances in the field and necessary steps to move a vaccine concept into a trial and onward toward licensure. The session featured two case studies looking at what comes after an efficacy signal, the many issues along the difficult road to licensure (the RV144 trial) as well as the steps and considerations to plan and execute a phase IIb trials, using HVTN 505 as an example.
Plenary Session 02
Title: A New Look at the Transmission Event
Plenary Chairs: Margaret McGlynn and Bruce Walker
Poster Discussions by IAVI and Partners
Title: Uptake and tolerability of repeated mucosal specimen collection in two Phase 1 AIDS preventive vaccine trials in Kenya
Authors: J. Mukamuyango , E. Karita, R. Bayingana, J. Nyombayire, R. Ingabire, S. Claudia, P. Fast , M. Price, A. Tichacek, S. Allen
Poster Presentations by IAVI and Partners
Title: Development of chimeric HIV Env immunogens for mucosal delivery with attenuated canine distemper virus (CDV) vaccine vectors
Authors: X. Zhang, S. Richlak, H.T. Nguyen, O. Wallace, G. Morrow, M. Caulfield, C. Parks
Title: Evaluation of a Replication-Competent VSV-SIV Vaccine Candidate
Authors: C. Jurgens, G. Morrow, C. Boggiano, M. Panis, J. Coleman, R. Powell, M. Yuan, M. Kemelman, N. Tamot, M. Lopez, A. Ouattara, S. Iyer, M. Backer, K. Wright, A. Domi, M. Chiuchiolo, C.R. King, M. Caulfield, C.L. Parks
Title: Alcohol and illicit drug use among potential HIV vaccine efficacy trial volunteers along Lake Victoria, Uganda
Authors: I. Ssekandi, A. Ssetaala, J. Mpendo, A. Nanvubya, L. Nielsen, N. Kiwanuka
Title: Willingness to participate in HIV vaccine trials in a potential efficacy trial population of fishing communities, Uganda
Authors: A. Nanvubya, J. Mpendo, A. Ssetaala, W. Kidega, S. Sigirenda, L. Nielsen, N. Kiwanuka
Title: Are fishing communities another most-at-risk-population? Results of a community based study along Lake Victoria, Uganda.
Authors: A. Ssetaala, J. Mpendo, A. Nanvubya, S. Sigirenda, L. Nielsen, N. Kiwanuka
Title: Development of candidate HIV vaccines using VSV vectors to express membrane-anchored MPER immunogen
Authors: M. Yuan, A. Wilson, M. Kemelman, M. Panis, I. Lorenz, C. Jurgens, M.J. Chiuchiolo, C.R. King, M. Caulfield, C.L. Parks
Title: Optimizing expression of functional HIV Envelopes in rVSV-ΔG vaccine vectors
Authors: K. Wright, M. Yuan, A. Wilson, C. Boggiano, J.Coleman, M. Kemelman, P. Tiberio, S. Phogat, I. Lorenz, S. Hoffenberg, C. Jurgens, C.R. King, M. Caulfield, C.L. Parks
Title: Viral vector delivery of Env trimer immunogens
Authors: C.L. Parks, S. Rabinovich, P.J. Tiberio, K.J. Wright, M. Yuan, M. G. Delboy, M. Kemelman, A.J. Wilson, R. Powell, S. Hoffenberg, M.J. Chiuchiolo, C. Boggiano, G. Morrow, C.K. Jurgens, X. Zhang, R.W. Lindsay, W.C. Koff, C.R. King, and M.J. Caulfield
Title: Inverse dose-response to gp140 YU2 foldon trimer formulated with aluminum phosphate and ISCOMATRIX® adjuvants
Authors: A. Wilson
Title: Tolerability and Acceptability of Electroporation at first vaccination time point during a phase I HIV Vaccine Trial at two sites in Uganda and Rwanda
Authors: J.Mpendo, R. Bayingana, A. Nanvubya, E. Karita, A. Ssetaala, N. Kiwanuka, J. Lehrman, C. Schmidt, D. Hannaman, S. Allen, P. Fast
Title: Developing standards of care for HIV prevention research in Africa – A case study of ten research centers in Eastern and Southern Africa
Authors: P. Bahati, B. Bender, F. Priddy, H. Park, J. Becker, P. Fast, O. Anza la, G. Mutua, E. Ruzagira, A. Kamali E. Karita, P. Mugo, E.Chomba, L.G. Bekker, S. Roux, A. Nanvubya, T. Mebrahtu
Title: Training trial staff in the use of a mixed method Assessment of Understanding tool in HIV vaccine trials.
Authors: J. Mbogua, T. Mebrahtu, G. Lindegger, S. Welsh, O. Anzala, G. Mutua, J. Mpendo, E. Karita, S. Singh
Title: Electroporation (EP) technical errors experienced during the enrolment period of an HIV Vaccine Clinical Trial at two sites in Rwanda and Uganda: Lessons learned
Authors: R. Bayingana, A. Nanvubya, E. Karita, J. Nyombayire, R. Ingabire, J. Mpendo, J. Lehrman, C. Schmidt, D. Laufer, K. Chinyenze, D. Hannaman, S. Allen, P. Fast
Title: HIV Disease Progression compared by Linkage status in Rwanda and Zambia
Authors: W. Kilembe, C. Dinh, S. Lakhi, E. Karita, R. Bayingana, M. Price, S. Allen, E. Hunter
Title: Priming with DNA Encoding Functional Trimers and Boosting with Soluble Trimeric Protein Elicited Tier 2 Neutralizing Antibodies in Non-human Primates
Authors: B.K. Chakrabarti, Y. Feng, K. McKee, C. Labranche, D. Montefiori, J.R. Mascola R.T. Wyatt
Oral Presentations by IAVI and Partners
Title: Identification of a clade A HIV envelope immunogen from Protocol G that elicits neutralizing antibodies to Tier 2 viruses
Authors: S. Hoffenberg, S.K. Pond, A. Carpov, D. Wagner, A. Wilson
Title: A Mixed-methods Assessment of Understanding (AoU) tool for AIDS vaccine trials in sub-Saharan Africa: Results from a Pilot study
Authors: G. Lindegger, M. Quayle, S. Singh, S. Welsh, D. Mark, M. Wallace, L.G. Bekker, S. Roux, L. Mwananyanda, W. Kilembe, F. Priddy, P. Fast
Title: Vaccine Responses to Conserved Regions of the HIV-1 Proteome are Associated with an Increased Capacity to Inhibit Multiple Virus Isolates Ex Vivo
Authors: A. Ashraf, J. Kopycinski, H. Cheeseman, F. Lala, J. Czyzewska-Khan, A. Spentzou, D.K. Gill, M. Keefer, J.L. Excler, P. Fast, P. Hayes, J. Cox and J. Gilmour
Title: An assessment of Good Participatory Practice Guidelines at HIV prevention research clinical centers in Eastern and Southern Africa – perceptions, effective practices, and areas of improvements.
Authors: P. Bahati, S. Hannah, J. Mbogua, M. Seyoum, M. Warren, E. Bass, P. Frances
Title: New Tools to Measure Community and Stakeholder Engagement and its Impact on Outcomes of Clinical Research
Author: P. Bahati
Partner Presentations
Title: A Short Segment in the HIV-1 gp120 V1/V2 Region Is a Major Determinant of Neutralization Resistance to PG9-Like Antibodies
Authors: N.A. Doria-Rose, I. Georgiev, R.P. Staupe, S. O’Dell, G.Y. Chuang, J. Gorman, J.S. McLellan, M. Pancera, M. Bonsignori, B.F. Haynes, D. R. Burton, W.C. Koff, P.D. Kwong, J.R. Mascola
Title: Vector induced skewing of antibody Fc-effector functions
Authors: A.W. Chung, A.S. Dugast, H. Robinson, Y. Chan, M.E. Ackerman, J. Cox, W.e Koff, D. Barouch, N. Michael, J. Kim, and G. Alter
Title: Development of Adenovirus Serotype 4 Replicating Vector Vaccine Expressing HIV-1 Env gp160 1086.C
Authors: B. Guenther, C.LaBranche, D. Montefiori, H.X. Liao, B. Haynes, M. Gurwith, J. Smith, T. Mayall